ea0032p1108 | Thyroid cancer | ECE2013
Tobias Balint
, Balla Bernadett
, Kosa Janos P
, Horanyi Janos
, Takacs Istvan
, Nagy Zsolt
, Horvath Peter
, Jaray Balazs
, Szekely Eszter
, Istok Roland
, Szekely Tamas
, Lakatos Peter
Cold nodules are one of the most common findings on scintigraphic examinations of the thyroid gland. About 510% of these nodules turn out to be histologically malignant. Our aim was to examine some somatogenetic alterations associated with thyroid cancer in FNA samples of the thyroid. These alterations included single nucleotide mutations (BRAF, HRAS, NRAS, KRAS) and genetic translocations (RET/PTC1, RET/PTC3, PAX8ex7/PPARgamma, PAX8ex9/PPARgamma). The SNPs were tested b...